Molecular Genetic Analysis of Poliovirus Infection
نویسندگان
چکیده
منابع مشابه
Molecular aspects of poliovirus pathogenesis
The development of a transgenic mouse model carrying the human poliovirus receptor has made it possible to investigate the molecular mechanisms of the viral dissemination process in a whole organism. Studies on this have provided an insight into the mechanisms for viral permeation through the blood-brain barrier and retrograde axonal transport of the virus. In addition, strain-specific neurovir...
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Poliovirus is a single stranded RNA virus, a member of the family Picornaviridae, genus poliovirus. There are three strains poliovirus types 1-3. Poliovirus is an important cause of acute flaccid paralysis (AFP), which when attributable to poliovirus is known as paralytic poliomyelitis. Paralytic poliomyelitis follows approximately 0.1-2% of poliovirus infections and typically presents as an ac...
متن کاملMolecular weight of poliovirus ribonucleic acid.
Purified poliovirus single- and double-stranded ribonucleic acids (RNA) were examined by electron microscopy. The length of both molecules was found to be 2.37 mum. The uncorrected sedimentation coefficient for single-stranded RNA is 33S, as compared to 27S for the RNA of tobacco mosaic virus. It is calculated from these results that the molecular weight of the sodium form of poliovirus is 2.6 ...
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Background: Sexual reproduction affords the stands for conserving genetic characteristics and sequentially, genetic inconsistency may influence the capability to imitate. Materials and Methods: Research was conducted by subject in PubMed and other databases. Results: A significant number of genotypes have been related with infertility phenotypes and evaluation of precise genes in humans and mod...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 1989
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi1947.109.9_622